Connecting patients, sites, and sponsors through one intelligence engine.
A $87B industry runs on manual matching, fax-based outreach, and infrastructure built for a different decade. The patients exist. The trials exist. The intelligence layer connecting them does not.
Modular by design. Start with what you need, add modules as you scale. From SMOs running portfolios of trials to patients searching for the trial that fits.
Auto-screens your entire patient database, determines protocol eligibility, and makes initial screening calls. Reads structured and unstructured EMR data — progress notes, faxes, PDFs.
AI parses protocols and patient charts automatically. Auto-populates patient records and CRFs. CDISC TMF-aligned document management with SMO-native hierarchy.
Real-time milestone tracking, visit scheduling, and trial-wide coordination. One command center across every protocol, every site, every sponsor.
Auto-generates invoices when trial events occur. Sponsor-to-site payment orchestration with automatic reconciliation. Zero manual billing overhead.
One centralized active patient database. Match patients across all open trials. AI ranks candidates by protocol fit and historical engagement.
Integrated sponsor outreach, opportunity tracking, and proposal management. Built for SMO growth teams that need to win more trials, not just run them.
Submit any protocol PDF — receive structured eligibility criteria, visit schedules, and budget breakdowns ready to deploy. Per-protocol pricing.
Automated electronic source document generation from your visit data. Audit-ready, regulator-compliant, sponsor-formatted.
On-demand structured datasets compiled from your patient records — for sponsor reporting, regulatory submissions, or internal analytics.
End-to-end encryption, role-based access, full audit logs. Built on AWS with regional redundancy and 21 CFR Part 11-ready architecture.
Connect to Epic, Cerner, and other EMRs. Bi-directional sync with sponsor systems and contact tools like Apollo for outreach.
Buy only the modules you need. Add more as you scale. Per-patient performance fees on recruitment. No six-figure annual contracts required.
Your patient population is matched against active trials without PHI ever leaving your system. AI identifies eligible cohorts using de-identified records only.
See what happens to the patients you refer. Structured outcome summaries are returned after trial completion — closing the loop on continuity of care.
Generate new revenue from a population you already serve. Fair-market-value compensation for chart review, screening coordination, and outreach.
Equip your physicians with a tool to find relevant trials at the point of care. Match patient diagnosis and history against open studies in seconds.
Digital consent workflows, scheduling, and patient handoff to research sites. No new staff required — esslead handles the coordination.
Plugs into Epic, Cerner, athenahealth, and other systems you already use. No data migration. No parallel database. No new logins.
Real-time recruitment performance, screen failure analysis, and site benchmarking across your entire portfolio. The dashboard CTMS has been promising for 20 years.
AI ranks sites by actual patient pool fit, historical enrollment velocity, and protocol match. Replaces manual feasibility studies with network-scale data.
Identify eligibility criteria likely to slow enrollment before activation. Cross-network analysis of historical trial outcomes flags amendable protocol elements.
Run synthetic trial simulations against de-identified network cohorts before activating sites. Test protocol amendments without burning real screen failures.
Predict enrollment timelines before contracts are signed. Cross-network historical data delivers actuarial-grade enrollment forecasts.
Aggregate, structured reporting across every site running your trial. No more chasing weekly status reports from CRAs.
Find clinical trials matched to your medical history, not just your zip code. AI matching based on full chart context, not just diagnosis codes.
Schedule visits, sign consent forms, get visit reminders — all in one place. Multilingual support and accessibility built in from day one.
Track stipends, mileage, and reimbursements in real time. Transparent payment timelines — no more wondering when or whether you'll be paid.
Receive structured updates on trial outcomes and ongoing care continuity. Your participation contributes to the next match for the next patient.
esslead is not a tool sold to one customer. It is a network that gets more valuable as it grows. Fills trials faster. Finds sites that fit. Turns patient populations into research access. Helps patients discover trials that could change their lives.
Every de-identified match, every screen failure, every protocol amendment becomes training data for a model that one day runs trials in silico, testing protocols against synthetic cohorts before a single patient is screened.
The first three layers are the product. The fourth layer is the asset. Each match made today trains the network for the trials of tomorrow.
esslead is reserving founding partner spots for SMOs, practice networks, and sponsors who want to shape what we build. In exchange for real-world validation, founding partners receive permanent preferred pricing, direct access to the founding team, and the ability to define our roadmap.
esslead is led by a team combining clinical trial domain expertise with deep AI capability — the combination CTMS has been missing. We're actively raising our seed round.
Joseph Mooney — CEO · Clinical. Former Clinical Research Coordinator at Yale. MS in neural engineering at the University of Miami. Previously operator at two clinical-trial-tech startups.
Sofya Levitina — COO · AI Scientist. Computational modeling and astrophysics (5+ yrs). AI scientist at a biotech firm working on aging and Alzheimer's. Clinical trial data architect with a sponsor-side perspective.
$200M US SMO software market, growing 12–14% annually. We are the only platform combining AI-native recruitment, document automation, and modular pricing — built for the buyer enterprise CTMS has ignored.
Active seed round underway. Pitch deck and financials available on request.
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